Dr. Holbrook was present at Fort Pierce on the night that it burned (December 11, 1843). His homestead was next to Captain Burnham on the south. He had come to the area from Charleston, South Carolina. Considered a talented physician he served the community for a time as a circuit riding doctor. Described as a man of powerful build, elderly, bald and usually hatless. He played flute and brought a valuable library with him to the settlement. He died after two years and was buried in an unmarked grave on the bluff.
- East Coast Florida Memoirs, 1837-1886, by Robert Ranson 1926.